The JPIAMR-VRI Joint Call Results – Eight Networks Funded

Eight networks have been awarded funding within the JPIAMR 2018 call for transnational networks “Building the Foundation of the JPIAMR Virtual Research Institute.” Each funded network will receive €50,000 to establish expertise clusters to identify research community needs and develop ideas to form the foundation for the JPIAMR Virtual Research Institute (JPIAMR-VRI).

The call was launched in May 2018 and supported by ten research-funding organisations from JPIAMR member countries. Fifteen applications were received, involving 15 coordinators and 323 partners.

To read more on the funded networks, please click here.

Results: JPIAMR Joint Call on Surveillance – Ten Networks Funded

Ten networks have been awarded funding within the JPIAMR 7th transnational call: “2018 Network Call on Surveillance”. Each funded network will receive €50,000 to enhance resource alignment and efforts in the field of AMR surveillance.

The call was launched in May 2018 and supported by ten research-funding organisations from JPIAMR member countries. Sixteen applications were received, involving 364 partners from 63 different countries.

To read more on the funded networks, please click here.

Results: Joint Call on New targets, compounds and tools – Ten Projects Funded

Ten projects have been awarded funding within the JPIAMR 6th transnational call: “Innovations against antibiotic-resistant bacteria: New targets, compounds and tools”. The total funding amount is 12,8 M€.

The call was launched in January 2018 and supported by 16 research-funding organisations from JPIAMR member countries. The primary aim of the call is to combine the resources, infrastructures, and research strengths of multiple countries in order to address the identification and validation of new targets, the development of new therapies, and new tools for new treatments (including new antibiotics).

104 applications were received, involving 468 partners. In total ten transnational projects were granted funding.

To read more on the funded projects, please click here.

Launch of Pew Trust’s Shared Platform for Antibiotic Research and Knowledge (SPARK)

Pew Trust has launched a publicly available interactive tool to provide data to help scientists around the world to identify urgently needed new antibiotics.

The pipeline of products in development to treat or prevent bacterial infections is stagnant and cannot meet today’s urgent and growing patient needs. Experts have repeatedly identified information sharing as essential to spurring innovation but have had difficulty benefiting from the insights of others.

Previously, there was no publicly available mechanism for sharing data and expertise across the antibiotic discovery research community. To help address these challenges, Pew created a cloud-based data-sharing tool called “SPARK”. It is a digital platform allowing researchers to share data, ideas, learn from past research and insights to spur the discovery of innovative new antibiotics needed in the battle against the growing global threat of drug-resistant bacteria or superbugs.

The information in SPARK is collected and curated by a team of antibiotic discovery experts and includes chemical and biological data relevant to understanding how molecules can get into Gram-negative bacteria and stay there, a critical factor in designing drugs that can defeat these increasingly hard-to-treat pathogens. SPARK integrates chemical and biological data from published studies as well as previously unpublished data, and provides an opportunity for real-time collaboration among scientists in industry, academia, government, and the nonprofit sector.

This information-sharing platform is of immense importance to JPIAMR and its funded researchers belonging to the antibiotic discovery community. SPARK provides antibiotic discovery data and cutting-edge analytics that will help JPIAMR generate and share new hypotheses and maximize the potential for developing new antibiotics.

To know more about the SPARK platform please read here.

JPIAMR Highlighted in G20 Health Ministers Joint Declaration

The 2018 G20 Health Ministerial Meeting in Mar del Plata, Argentina, concluded on October 4th with a joint declaration on concrete health policy proposals.

The document considers health a key aspect for sustainable development and calls for a further strengthening health systems. It also recommends concrete actions to address global issues such as antimicrobial resistance, and with commitments for “increasing the level of awareness on the prudent and responsible use and disposal of antibiotics of all healthcare providers, veterinarians, farmers and food producers and of the general public.”

In the declaration, the G20 also mentions JPIAMR together with GARDP, UNITAD, CARB-X and the TB-Alliance, welcoming the work of these leading international initiatives.

Please view the full declaration here.

Coming Soon: Call on Diagnostics and Surveillance

Antimicrobial resistance (AMR) has become one of the major global health and development challenges of the 21st century. The threat of AMR is particularly high in resource-limited and high-risk settings. This is linked to weak human and animal health systems; diverse means of food production, processing and consumption; food safety and food security; water, hygiene and sanitation challenges; and the global movement of people and goods.

In response to these challenges, the JPIAMR will launch a joint transnational call for proposals for innovative research projects on new or improved diagnostics and surveillance strategies, tools, technologies and methods. These research projects should address diagnosis of AMR infections in clinical and veterinary settings, or the emergence, surveillance, and/or detection of AMR in humans, animals and the environment. This Call will support research projects that also have the potential for impact in areas where the risk and burden of AMR is greatest, e.g. in LMIC settings in Asia and Africa. Projects are encouraged to use a One Health approach where relevant. The projected call budget is approx. 20 million Euro.

Scope of the call

Projects should aim to either:

  1. Develop strategies, tools, technologies, and methods for the detection, monitoring, profiling and/or surveillance of antimicrobial resistance and dynamics leading to resistance.
  2. Study ways to facilitate and implement the uptake and use of existing strategies, tools, technologies, and/or methods for the detection, monitoring, profiling and surveillance of antimicrobial resistance and dynamics leading to resistance.
Eligibility

List of participating countries is provisional.
Consortia of eligible scientists from participating JPIAMR member countries and eligible countries in Africa and Asia may apply to this call. Full eligibility criteria will be included in the Call launch. Participating JPIAMR member countries include Canada, Czech Republic, Finland, France, Germany, Israel, Italy, Latvia, Norway, Poland, Romania, Spain and  Sweden. Consortia must include a minimum of three and a maximum of six project partners from at least three eligible countries.

The Netherlands has the intention of joining the call but no funding is guaranteed yet. Updates on the progress will be shared.

Expected timeline
  • November 2018 – Pre-announcement of the call
  • December 2018 – Publication of the call
  • February 2019 – Submission deadline for pre-proposal
  • April 2019 – Full proposal invitations sent to project coordinators
  • June 2019 – Submission deadline for full proposals
  • October/November – Final funding decision announced
  • December 2019/ Early 2020 – Project start

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Joint Programming 10 year anniversary

In 2018 the Joint Programming Process (JPP) turns 10 years. This will be celebrated with a gala dinner in Vienna on the 19th of September, followed by a one-day conference on the 20th of September: 10 Years Joint Programming – Achievements and the Way Forward

The conference aims to gather the main stakeholders of the JPIs, to share their experiences in developing and implementing challenge-driven R&I programmes and exchange on possible contributions towards Sustainable Development Goals. JPIAMR will be presenting regarding the JPIAMR-Virtual Research Institute.

For more information and draft agenda, please click here.

Launch of Global AMR R&D Hub

In 2017, the G20 heads of state and government took the decision to intensify global collaboration in the fight against AMR. The German Federal Ministry of Education and Research (BMBF) then proposed plans for a Global Antimicrobial Resistance Research and Development Hub – or Global AMR R&D Hub for short.

The Hub was launched on 22 May coinciding with the World Health Assembly in Geneva. The Hub aims to improve further the coordination of international efforts and initiatives to tackle AMR while further increasing investments into R&D for AMR.

The secretariat of the Global AMR R&D Hub will be based in Berlin, at the German Center for Infection Research (DZIF). The BMBF will provide up to 500 million euros over the next ten years towards research to combat antimicrobial resistance. JPIAMR has taken part of the consultation regarding their workplan.

Read more

Discussion papers informing the report of IACG to the UN Secretary-General

The Interagency Coordination Group on Antimicrobial Resistance was formed in 2016 with the mandate to provide practical guidance for approaches needed to ensure sustained effective global action to address antimicrobial resistance; and to report back to the UN Secretary-General in 2019.

Over the last year JPIAMR has been collaborating with the IACG subgroup on innovation, R&D and access, with the aim of reporting to the UN Secretary-General.

To date, six discussion papers have been prepared by the IACG, and over the summer, the IACG launched a web-based public consultation to solicit feedback from all interested stakeholders.

To read more and to download the discussion papers, please click here.